diff --git a/docs/changelog.rst b/docs/changelog.rst
index f17bb0a5b..52010cbff 100644
--- a/docs/changelog.rst
+++ b/docs/changelog.rst
@@ -186,6 +186,7 @@ Detailed list of changes
 
 - The :opt:`show_hyperlink_targets` option now allows specifying a keyboard modifier so that target URLs are only shown on hover when the modifier is pressed (:pull:`9741`)
 
+- Fix a spurious mouse button release event being sent when dragging out of an OS window causes focus loss
 
 0.46.2 [2026-03-21]
 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
diff --git a/glfw/window.c b/glfw/window.c
index 652034fbe..2eebfcbbb 100644
--- a/glfw/window.c
+++ b/glfw/window.c
@@ -63,8 +63,14 @@ void _glfwInputWindowFocus(_GLFWwindow* window, bool focused)
 
         for (int button = 0;  button <= GLFW_MOUSE_BUTTON_LAST;  button++)
         {
-            if (window->mouseButtons[button] == GLFW_PRESS)
+            if (window->mouseButtons[button] == GLFW_PRESS) {
+                // Skip releasing the left mouse button when a drag is in
+                // progress from this window to avoid spurious release events.
+                // The release will be sent after the drag completes.
+                if (button == GLFW_MOUSE_BUTTON_LEFT && _glfw.drag.window_id == window->id)
+                    continue;
                 _glfwInputMouseClick(window, button, GLFW_RELEASE, 0);
+            }
         }
     } else
         _glfw.focusedWindowId = window->id;