diff --git a/docs/changelog.rst b/docs/changelog.rst
index f17bb0a5b..52010cbff 100644
--- a/docs/changelog.rst
+++ b/docs/changelog.rst
@@ -186,6 +186,7 @@ Detailed list of changes
 
 - The :opt:`show_hyperlink_targets` option now allows specifying a keyboard modifier so that target URLs are only shown on hover when the modifier is pressed (:pull:`9741`)
 
+- Fix a spurious mouse button release event being sent when dragging out of an OS window causes focus loss
 
 0.46.2 [2026-03-21]
 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
diff --git a/glfw/input.c b/glfw/input.c
index 9ded16610..7f24f2137 100644
--- a/glfw/input.c
+++ b/glfw/input.c
@@ -1160,6 +1160,7 @@ GLFWAPI GLFWdragsourcefun glfwSetDragSourceCallback(GLFWwindow* handle, GLFWdrag
 
 void
 _glfwFreeDragSourceData(void) {
+    GLFWid drag_window_id = _glfw.drag.window_id;
     _glfwPlatformFreeDragSourceData();
     if (_glfw.drag.items) {
         for (size_t i = 0; i < _glfw.drag.item_count; i++) {
@@ -1171,6 +1172,15 @@ _glfwFreeDragSourceData(void) {
     GLFWid iid = _glfw.drag.instance_id;
     memset(&_glfw.drag, 0, sizeof(_glfw.drag));
     _glfw.drag.instance_id = iid;
+    // Send a synthetic left button release to the drag source window if the
+    // button is still marked as pressed. The focus-loss release was suppressed
+    // while the drag was in progress, and on some platforms (Wayland, Cocoa)
+    // the OS never sends a natural button release after the drag ends.
+    if (drag_window_id) {
+        _GLFWwindow* drag_window = _glfwWindowForId(drag_window_id);
+        if (drag_window && drag_window->mouseButtons[GLFW_MOUSE_BUTTON_LEFT] == GLFW_PRESS)
+            _glfwInputMouseClick(drag_window, GLFW_MOUSE_BUTTON_LEFT, GLFW_RELEASE, 0);
+    }
 }
 
 GLFWAPI int
diff --git a/glfw/window.c b/glfw/window.c
index 652034fbe..2eebfcbbb 100644
--- a/glfw/window.c
+++ b/glfw/window.c
@@ -63,8 +63,14 @@ void _glfwInputWindowFocus(_GLFWwindow* window, bool focused)
 
         for (int button = 0;  button <= GLFW_MOUSE_BUTTON_LAST;  button++)
         {
-            if (window->mouseButtons[button] == GLFW_PRESS)
+            if (window->mouseButtons[button] == GLFW_PRESS) {
+                // Skip releasing the left mouse button when a drag is in
+                // progress from this window to avoid spurious release events.
+                // The release will be sent after the drag completes.
+                if (button == GLFW_MOUSE_BUTTON_LEFT && _glfw.drag.window_id == window->id)
+                    continue;
                 _glfwInputMouseClick(window, button, GLFW_RELEASE, 0);
+            }
         }
     } else
         _glfw.focusedWindowId = window->id;